Enrichment Bubble Plot

Visualize GO/KEGG over-representation analysis (ORA) results. Bubble size encodes gene count, color encodes significance (-log10 FDR), x-axis shows gene ratio.

Visualization Parameters

Upload enrichment analysis results and generate the bubble plot

Upload Data File

TSV/CSV with Term, GeneRatio (or Count) and p.adjust columns

Required Files

data.tsv — Enrichment results: Term, GeneRatio, Count, p.adjust

Format

Row = one enriched term / pathway
Term: GO term or pathway name (aliases: Description, Pathway)
GeneRatio: ratio like "25/300" (or provide Count instead)
Count: number of genes in the term (bubble size)
p.adjust: adjusted P value (aliases: FDR, qvalue, pvalue)
Top 20 terms by significance are shown

Enrichment Data

Term	GeneRatio	Count	p.adjust
Fatty acid degradation	38/450	38	1.2e-09
HIF-1 signaling pathway	32/380	32	4.5e-08
PPAR signaling pathway	28/320	28	2.1e-07
Circadian rhythm	22/260	22	3.6e-06

Enrichment Bubble Plot

Upload data and click Generate, or run with example data

Documentation

Input format: a table of enrichment analysis results. Required: a term name column (Term/Description/Pathway), a significance column (p.adjust/FDR/pvalue), and either GeneRatio (e.g., "25/300") or Count.

Reading the plot: larger bubbles = more genes; redder color = more significant; further right = higher gene ratio. Compatible with clusterProfiler, DAVID and Metascape result tables.

Typical use: downstream of differential expression analysis (RNA-seq workflow, Comparative Hibernomics) — a companion to the GSEA Plot tool.