Methylation Meta-Profile

Plot average methylation (or any signal) along normalized genomic coordinates — for example ±2 kb around transcription start sites — with per-group mean curves and variability ribbons.

Visualization Parameters

Upload your data and generate the methylation meta-profile

Upload Data File

TSV/CSV long table: Position, Value, optional Group

Required Files

profile.tsv — long table: Position (coordinate), Value (signal), optional Group

Format

Row = one measurement of one region at one position
Position: normalized coordinate (e.g., -2000..2000 around TSS)
Value: methylation level or signal intensity (aliases: Methylation, Signal, Score)
Group (optional): condition label — one curve per group
Values are averaged per Position × Group; ribbon = ± SD

Example Data

Position	Value	Group
-2000	72.05	Active
-1950	66.95	Active
-1900	66.75	Active
-1850	71.91	Active

Methylation Meta-Profile

Upload data and click Generate, or run with example data

Documentation

Input format: long table with Position, Value and an optional Group column. Each row is one observation; the script aggregates mean ± SD per position and group.

Interpretation: the dashed vertical line marks position 0 (e.g., the TSS). A dip around 0 is characteristic of promoter hypomethylation.

Typical use: compare methylation meta-profiles between Active and Torpor states from the Epigenomics workflow.